Fildena pills, containing sildenafil citrate, work as a potent treatment for erectile dysfunction (ED) by targeting the underlying physiological mechanism that causes impotence. Understanding the mechanism of action of Fildena can help shed light on how it enhances erectile function. Here's how Fildena works:
1. Phosphodiesterase Type 5 (PDE5) Inhibition: The main active ingredient in Fildena, sildenafil citrate, belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. PDE5 is an enzyme found primarily in the smooth muscle cells of the penis and other areas of the body.
2. Nitric Oxide Release: When a man is sexually aroused, nerve signals stimulate the release of nitric oxide (NO) in the penile tissues. Nitric oxide actuates a chemical called guanylate cyclase, which builds the degrees of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis.
3. Smooth Muscle Relaxation: Increased cGMP levels cause the smooth muscle cells in the penile blood vessels to relax. As a result, the blood vessels dilate, allowing more blood to flow into the penile tissues, and the penile arteries expand.
4. Enhanced Blood Flow: The increased blood flow into the penis results in engorgement and swelling of the erectile tissues. This process leads to the formation of a firm and a sustained erection that is suitable for sexual intercourse.
5. PDE5 Inhibition by Sildenafil: However, in men with erectile dysfunction, the enzyme PDE5 breaks down cGMP, limiting the amount of cGMP available to maintain the erection. Fildena 150 works by inhibiting PDE5, preventing it from breaking down cGMP. This inhibition allows cGMP levels to remain elevated for a more extended period, promoting prolonged and improved blood flow to the penis.
6. Sexual Stimulation Required: It is important to note that Fildena's mechanism of action requires sexual stimulation to trigger the release of nitric oxide. The medication does not cause spontaneous erections but enhances the body's natural response to sexual arousal.
7. Duration of Action: Fildena's effect typically lasts for about 4 to 6 hours after ingestion, during which time sexual activity can be initiated and sustained. It is essential to remember that Fildena 100 is not a cure for erectile dysfunction but provides temporary relief from its symptoms.
Conclusion:
Fildena pills work by inhibiting the enzyme PDE5, allowing for increased cGMP levels and enhanced blood flow to the penis during sexual stimulation. This mechanism of action promotes the ability to achieve and sustain firm erections, helping men with erectile dysfunction regain their sexual confidence and intimacy. However, it is essential to use Fildena as prescribed by a healthcare professional and be aware of potential side effects and safety considerations. Always consult with a qualified healthcare professional before starting any medication, including Fildena, to ensure its appropriateness for your individual health needs and circumstances.
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