The amount of muscle tissue (muscle mass) and muscle strength tend to decrease beginning around age 30 and continuing throughout life. Some of the decrease is caused by physical inactivity and decreasing levels of growth hormone and testosterone, which stimulate muscle development. Also, muscles cannot contract as quickly because more fast-contracting (fast-twitch) muscle fibers are lost than slow-contracting (slow-twitch) muscle fibers. However, aging's effects reduce muscle mass and strength by no more than about 10 to 15% during an adult's lifetime. In the absence of disease, most of the loss beyond that 10 to 15% is preventable with regular exercise. More severe muscle loss (called sarcopenia, which literally means loss of flesh) results from disease or extreme inactivity, not from aging alone.