Many Americans are familiar with the opioid epidemic headlines dominating the news. A likely byproduct of the overall disruptions and stress induced by the COVID-19 pandemic, preventable opioid overdose deaths increased 41% in 2020 and another 18% in 2021. The 35- to 44-year age group is experiencing the most opioid overdose deaths – 20,137 – a 20% increase from 2020, and a 73% increase since 2019. Currently, 71% of preventable opioid deaths occur among those ages 25 to 54, and the number of deaths among individuals 55 and older is growing rapidly. Few opioid deaths occur among children younger than 15.