The ECS is a neuromodulatory system of metabolism, consisting of cannabinoid receptors (CB or RCB), endocannabinoids, also called ligands, and reuptake enzymes, biosynthesis, transport, and degradation proteins.
The endocannabinoid system: Endocannabinoid is understood as any lipid molecule belonging to the group of terpenophenols. These potent SEC ligands have been described from photo structures such as cannabis (cannabis Sativa), which began to be studied in the 1960s and is currently postulated to have a homeostatic regulation relationship in intake and metabolism.
Energy metabolism: In later years, the cloning of CBS in mammalian cells allowed the identification of their endogenous ligands. Arachidonoylethanolamide (N-arachidonic ethanolamine or AEA or anandamide) is the first CB ligand identified. They were followed by 2-arachidonoyl glycerol (2-AG).
CB ligands regulate various aspects of brain functions such as memory, learning, synaptic transmission, and different forms of short- and long-term plasticity. In addition to influencing growth and development processes, such as synapses and neurogenesis. Endocannabinoids modulated other biological functions, including anxiety, appetite, inflammation, and pain.
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The phytocannabinoids are Δ-9-tetrahydrocannabinol, cannabidiol (CBD), and ajulemic acid. These compounds act as agonist ligands of CB type 1 (RCB1 or CB1) and CB type 2 (RCB2 or CB2) in the central nervous system (CNS), as well as in organs with peripheral nerve innervation. Regarding its synthesis, one of its leading promoters is the ionic concentration of extracellular Ca2+, since N-acetyltransferase and N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) are Ca2+-dependent enzymes.
In parallel, the enzymes diacylglycerol lipase and phospholipase C are responsible for the synthesis of 2-AG. It is essential to mention that, under physiological conditions, AEA and 2-AG are synthesized on "demand" during cell membrane remodeling and rapidly degrade. They have a localized and transient effect. Medicinal australia plants have herbal properties.
Once upon a time, every herb, annual or perennial species whose aerial parts were green and of a non-woody consistency, was defined as a medicinal plant. Every plant, shrub, and tree is used in the apothecary's workshops. The forerunners of pharmaceutical laboratories mastered the techniques of processing plants, the numerous preparation procedures for oils, ointments of all kinds, perfumes, blends, and created cosmetic remedies for daily well-being or medicaments for therapeutic or preventive purposes.
Properties of herbs
Each plant has specific properties depending on which part of the plant is used. Different parts of the same plant, such as the root, leaf, flower, fruit, bark, or bud, can be used for health purposes depending on the active ingredients contained. The number of active ingredients present in the part of the plant in question can vary and reaches the maximum level during the balsamic time, the optimal time for harvesting.
The effectiveness of a plant depends both on the balsamic time and the place where it is harvested. Growing in an unpolluted area is essential, away from roads, sewers, landfills, factories, and intensive cultures. Even today, medicinal herbs prove to be a considerable family of plants used to preserve the health and well-being of those who fully understand its value. Medicinal herbal clinic used aromatic plants for treatment.
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