Jurkat Cells

Jurkat cells are a human T-lymphocyte leukemia cell line derived from a 14-year-old with T-cell acute lymphoblastic leukemia (T-ALL). Widely used in research, they’re integral to studies on immune signaling, T-cell activation, HIV infection (via CD4 receptor), autophagy, cytotoxicity assays, and drug efficacy. Jurkat derivatives like E6.1 enhance investigations into signaling pathways and membrane dynamics.